Solenna isn't a magic pill or a brain game with a health promise. It's an evidence-based way to know the risk factors you can change and train the cognitive skills the research points to — tracked over time. Here's exactly what that's grounded in.
Four bodies of evidence shape the product. We're inspired by them — Solenna itself is not a clinical trial, and we don't claim it is.
The standing Commission on dementia concluded that around 45% of dementia cases are associated with 14 modifiable risk factors across the life course — from blood pressure and hearing to activity, mood, and social contact. Your risk profile is built directly on these.
Livingston et al., The Lancet, 2024.A two-year multidomain lifestyle programme — diet, exercise, cognitive training, and vascular monitoring together — improved or maintained cognition in at-risk older adults versus control. This is why Solenna is a stack of levers, not one trick.
Ngandu et al., The Lancet, 2015.Over a 10-year follow-up, speed-of-processing training was linked to a lower risk of dementia — the strongest cognitive-training signal to date. Processing speed is the anchor of your daily brain workout.
Rebok et al., 2014; Edwards et al., Alzheimer's & Dementia (TRCI), 2017.The LIBRA index (Deckers et al., 2015) is the weighted list your risk profile is actually scored against. It was built to rank modifiable factors for an individual, which the Lancet Commission's population estimate is not designed to do. An updated version with revised weights was published in 2024 and Solenna has not migrated to it yet. Naming it here because it does the scoring work and was previously the one source on this page we did not credit.
Intensive blood-pressure control significantly reduced the risk of mild cognitive impairment versus standard control. What's good for your heart is good for your brain — a core Solenna lever.
SPRINT MIND Investigators, JAMA, 2019.Our pledge, in plain terms: we say reduce risk, lower risk, delay onset, and may help. We never say prevent, cure, treat, reverse, or diagnose. Solenna is educational — it informs and helps you build habits linked to lower risk. It is not a medical device, a diagnosis, or a guarantee, and individual results vary.
If a claim can't be backed by the evidence above, we don't make it.
Free, private, no diagnosis. Your risk profile picks the levers that matter most for you.